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We've known for years now that Lyme and related pathogens have caused health issues outside of the telltale "Erythema Migrans" or bullseye rash. Several "specials" on local public tv and radio stations have done pieces showing the effects on the large joints affected, the knee being one of the most documented with surgery for knee replacement. In more recent publications, Lyme carditis is being recognized as one of the early issues with Lyme bacteria as well.