Lyme Disease Coalition Inc.
  • Home
  • News
  • Calendar of events
  • Contact
  • Education
    • Videos, Books, & Materials
  • Prevention
    • Tick Off! Tick aid Kit
    • Prevention tips
    • Repellents, Clothing & Yard Treatments >
      • BugBeWear
    • Sawyer Products
  • Corporate Sponsors
  • Research
    • Studies Research & Testing >
      • Columbia Lyme Treatment Study
      • Borrelia Test Evaluation
  • Support
    • Patient Care Providers
    • Lyme Scout
    • Other Site and Group Links >
      • Links to support groups
      • Links to other Resources >
        • Lyme Aid 4 Kids
        • Lyme Disease Association LDA
        • Lyme Disease Org.
        • Under Our Skin
  • Treatments
    • Testing for Humans
    • National Guideline Clearinghouse Treatment Guidelines
    • Treatments by qualified Professionals
    • What is Lyme
  • Tick Testing
  • Lyme legisation
  • About us
    • About LDC
    • Our Support Committees
  • Find us on FaceBook!
  • Patient Blog
  • Link Page
  • Surveillance
  • Home
  • News
  • Calendar of events
  • Contact
  • Education
    • Videos, Books, & Materials
  • Prevention
    • Tick Off! Tick aid Kit
    • Prevention tips
    • Repellents, Clothing & Yard Treatments >
      • BugBeWear
    • Sawyer Products
  • Corporate Sponsors
  • Research
    • Studies Research & Testing >
      • Columbia Lyme Treatment Study
      • Borrelia Test Evaluation
  • Support
    • Patient Care Providers
    • Lyme Scout
    • Other Site and Group Links >
      • Links to support groups
      • Links to other Resources >
        • Lyme Aid 4 Kids
        • Lyme Disease Association LDA
        • Lyme Disease Org.
        • Under Our Skin
  • Treatments
    • Testing for Humans
    • National Guideline Clearinghouse Treatment Guidelines
    • Treatments by qualified Professionals
    • What is Lyme
  • Tick Testing
  • Lyme legisation
  • About us
    • About LDC
    • Our Support Committees
  • Find us on FaceBook!
  • Patient Blog
  • Link Page
  • Surveillance
Search by typing & pressing enter

YOUR CART

Picture

This website uses marketing and tracking technologies. Opting out of this will opt you out of all cookies, except for those needed to run the website. Note that some products may not work as well without tracking cookies.

Opt Out of Cookies

10/23/2017 Comments

PRESS RELEASE - IGeneX-Introduces-New-Diagnostic-Tests-Lyme-Disease

Press Release 

October 16, 2017 
Source: http://www.businesswire.com/news/home/20171016005904/en/IGeneX-Introduces-New-Diagnostic-Tests-Lyme-Disease 
or http://tinyurl.com/y9d9hzxd 


Palo Alto, CA -- IGeneX Inc., a CLIA and New York-approved Reference Laboratory, specializing in testing for tick-borne diseases, is pleased to announce the launch of three new tests that are more inclusive and specific for aiding in diagnosis of Borreliosis (Lyme Disease and Tick-Borne Relapsing Fever, Borreliosis). 
Lyme ImmunoBlot IgM and IgG TBRF ImmunoBlot IgM and IgG Lyme IGX Spot https://www.igenex.com/testing/diagnostic-tests-for-borrelliosis/lyme-igxspot-test/ 
Borreliosis is caused by two groups of Borrelia, B. burgdorferi group and the Tick-Borne Relapsing Fever (TBRF) Borrelia group. Until recently, it was believed that B. burgdorferi group was the only group that caused Lyme-like symptoms. However, we now know that TBRF Borrelia also causes Lyme-like symptoms. Therefore IGeneX developed two sets of Immunoblots, Lyme ImmunoBlot IgM and IgG and TBRF ImmunoBlot IgM and IgG. 

Many patients with Lyme-like symptoms are misdiagnosed because: (1) The current serological tests cannot detect antibodies to all the different strains of B. burgdorferi (2) For TBRF Borrelia, only two serological tests, an IFA test for B. hermsii and a serological test that detects only B. miyamotoi GlpQ protein, are available. In addition, with the increase in tick populations, Borreliosis is on the rise. Thus there is an urgent need for better diagnostic tests for Borreliosis. 

Because symptoms of Lyme and Tick-Borne Relapsing Fever are often similar, a more comprehensive battery of tests is critical for proper diagnosis. 

“IGeneX’s new Lyme ImmunoBlot and the TBRF ImmunoBlot tests are the first, most inclusive and specific serological tests for Lyme disease and TBRF,” said Dr. Jyotsna Shah, President and CEO of IGeneX. “These tests, when combined with Lyme IgX spot and PCR, cover the full spectrum of the disease." 

Lyme ImmunoBlots IgM and IgG 

Although IGeneX Lyme Western blot prepared from Borrelia burgdorferi strains B31 and 297 is one of the most sensitive tests, it does not detect antibodies to all the B. burgdorferi sensu lato antigens. To develop all inclusive Western blots would be very expensive and impractical. Therefore, IGeneX has developed a Lyme ImmunoBlot that is very specific and inclusive of most species of B. burgdorferi sensu lato for clinical use with the following advantages over a Western blot: 
The specificity of the ImmunoBlot is 98.0% for IgM and 98.7% for IgG. This is higher than the traditional Western Blot. The 31kDa Epitope confirmation test will not be required on patient samples tested by Lyme ImmunoBlots. The sensitivity of the Lyme Immunoblot is 90.9% with well-defined samples. The ImmunoBlot has better sensitivity compared tothe current Western Blot, because it is designed to detect antibodies to major B. burgdorferi sensu lato specific antigens from North America and European strains as listed below: 
B. burgdorferi B31 B. burgdorferi 297 B. californiensis B. mayonii B. afzelii B. garinii B. spielmanii B. valaisiana TBRF ImmunoBlots IgM and IgG 

The TBRF ImmunoBlot is designed to detect antibodies to specific antigens of TBRF Borrelia in human serum. It detects antibodies to B. hermsii, B. miyamotoi, B. turicatae and B. coriaceae. Based on in-house studies these blots detect antibodies to North American, European and Australian strains of TBRF Borrelia in patient serum samples. The specificity of the TBRF ImmunoBlot is 94% and 98% for IgM and IgG respectively. 

Lyme IGX Spot 

The Lyme IGXSpot is an Enzyme-Linked ImmunoSpot (ELISPOT) assay that detects human T cells reactive to B. burgdorferi specific antigens in vitro. ELISPOT is a widely used method for detecting and monitoring cellular immune responses to specific antigens. 

The Lyme IGX Spot test: 
Detects specific T-cell responses soon after B. burgdorferi infection, when antibodies to the organisms are not detectable or late in the disease, when the levels of antibodies are very low. When combined with Lyme ImmunoBlot tests, information on the full spectrum of patient’s immune response to infection and stage of disease is obtained. Is especially useful for seronegative patients. 
IGeneX Inc. 
https://www.igenex.com/ https://www.igenex.com/ 
795 San Antonio Rd, Palo Alto, CA 94303

Comments

    Author

    Colleen Schake
    Patient-​Living with Lyme
    Lyme Disease Coalition, Inc. - Founder
    Lyme Scout - Founder

    Archives

    November 2019
    March 2019
    February 2019
    January 2019
    October 2018
    June 2018
    May 2018
    April 2018
    March 2018
    November 2017
    October 2017
    July 2017
    June 2017
    May 2017
    April 2017
    March 2017
    January 2017
    December 2016

    Categories

    All Community Events Science For Cures

    RSS Feed

Powered by Create your own unique website with customizable templates.